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Symbol Name ID |
Apc
APC, WNT signaling pathway regulator MGI:88039 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Prostate cancer |
Ovarian carcinoma |
Endometrial carcinoma |
Uterine leiomyosarcoma |
| Disease(s) Associated with APC | ||||
| colorectal cancer | ||||
| endometrial cancer | ||||
| pancreatic cancer | ||||
| prostate cancer |
| Mouse Phenotypes | reproductive system phenotype |
absent male preputial gland |
prostate gland epithelial hyperplasia |
absent corpus luteum |
abnormal ovarian follicle morphology |
absent mature ovarian follicles |
abnormal ovarian folliculogenesis |
ovary atrophy |
ovary cyst |
increased ovary tumor incidence |
increased granulosa cell tumor incidence |
increased prostate gland adenocarcinoma incidence |
increased prostate intraepithelial neoplasia incidence |
increased reproductive system tumor incidence |
abnormal internal female genitalia morphology |
abnormal oviduct morphology |
endometrium hyperplasia |
uterus atrophy |
abnormal vagina epithelium morphology |
abnormal pregnancy |
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| Availability | Mouse Genotype | ||||||||||||||||||||
| Apctm1Rfo/Apctm1Rfo | |||||||||||||||||||||
| ApcMin/Apc+ | * | ||||||||||||||||||||
| Apctm1Rsmi/Apctm1Rsmi Pgrtm2(cre)Lyd/Pgr+ (conditional) |
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| Apctm1Tno/Apctm1Tno Tg(Pbsn-cre)4Prb/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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